Errata:

- Part 1, Page 5: I think "Lysosomal Hydrolases" are a class of enzymes, not just a single enzyme (they'd be any kind of hydrolase that is normally localized to the lysosome). A couple of the disease boxes on page 40 mention this - they seem to be relatively specific to a set or single substrate (not sure which).

- Part 2, Page 8: says "Cohesins are ubiqutinated at the onset of anaphase so the sister chromatids can separate".  I think page 111 has maybe the most clear explanation of this process, which is referred to several times - it seems that this APC thing (a ubiquitin ligase) is acually ubiquinating some protein called securin, which usually inactivates separase (a protease), which cleaves cohesin when set free of securin.  So it seems like cohesins are degraded by a ubiquitination-type pathway but not directly ubiquitinated themselves... although maybe it's said the other way around in another part of the notes.

-Please keep in mind that the GHK equation as written is for monovalent ions only (thanks Luke). 

- Part 5, Page 6:  Cross out "tight junctions" just before the asterisk.